The GeoLynch study is a prospective observational cohort study designed to investigate the relationship between dietary and lifestyle factors and the development of cancer among persons with Lynch syndrome. Because of the wide scope of the study a lot of specific research questions can be answered.
The study started in 2006 as part of a collaboration between Wageningen University, the Dutch Foundation for Detection of Hereditary Tumors (StOET) and the Gastroenterology and Hepatology departments of the Radboud University Medical Center in Nijmegen and the University Medical Center in Groningen. Between 2006 and 2008 about 500 persons with Lynch syndrome started to participate. At that time, we collected data on their dietary and lifestyle habits. Between 2012 and 2015 we collected follow-up data to examine if diet and lifestyle habits have changed over the years.
From 2012, we are also inviting more people with Lynch syndrome to participate. We aim to include 250 new participants, to expand the total cohort to 750 participants.
The GeoLynch study receives financial support from the Dutch Cancer Society (KWF Kankerbestrijding), the World Cancer Research Fund (WCRF) and BBMRI-NL. The study has been approved by the Central Committee on Research Involving Human Subjects of the region Arnhem-Nijmegen. You can find additional information under cooperation